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And there are countless doctors around the country who are seeing excellent results, although they are more focused on saving lives than running statistically valid randomized tests.
But the FDA got scared with a handful of coronary issues and other professed side effects....but the drug has been around treating malaria, lupus and rheumatoid arthritis for decades very successfully.
Hell, too much water has a terrible side effect...drowning.....
Any chemical you put in your body can do some harm...but under direction of a doctor who understands underlying medical conditions and the efficacy of the drug, it might be successful...many of the results certainly indicate as such.
But you are correct, Perfect-Circle...because Trump said it showed promise and what do we have to lose, the drug was immediately damned.
If Trump touted remdesivir we probably would be hearing about every side effect and problem and it would be poo pooed as well.
Of course, I heard that a full course of treatment of a patient with remdesivir could be up to $4460.
And the cost of hydroxychloroquine is like $25 for a supply of 60 tablets.....DUH.....
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there has not been any study that has reported that hydroxychloroquine is beneficial in the treatment of covid-19. There are anecdotal reports of possible benefit (Tom Hanks for one), but this is not scientific. There are better medications to focus time and effort teting on, medicine like Remdeivir (already approved), EIDD-2801, VIR-2703 and several others.
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^Did you bother to read what I wrote? Did you click on the link? A study is right there.
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A study.... Say no more Libtard...
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Yes, that was an obsevational study dipshit. Do a little reading so you undersand the difference between an observational study and an experimental study. THe observational study is essentially meaningless.
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the circle jerk has started, quick go get crane...
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Now, you can criticize the study. It's not randomized. It's not a clinical trial. It's not peer reviewed yet. But it's a study worth mentioning.
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"THe observational study is essentially meaningless."
Not true.
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In fact the all the studies that people like to quote showed no effect for hydroxychloroquine were "only" observational studies.
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I think it's great that options are being developed.
Necessity is the mother of invention. That's the American way.
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there are a lot of poorly conceived studies of this out, this journal article describes them all and is really what should be referenced for this discussion.
https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202000919
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An observational study is just that, a piece of evidence, but not enough. There's no need to get passive aggressive about this. Trump prescribed hydroxychloroquine, said there was evidence it worked, when in fact there was no conclusive evidence that it worked. That's irresponsible. None of this "Trump bad" shit. The FDA exists for a reason. Clinical trials exist for a reason. To filter out some of the snake oil. If you don't mind corporations paying doctors to give you procedures that are harmful to you can suck on Trump's left titty as a pacifier.
As for hydroxychloroquine, it might work, it might not. We need more evidence. Period.
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I am truly hoping that HCQ turns out to be an effective treatment with manageable side effects. That would help us get back towards a normal society and economy.
However, it wouldn't make Trump any less of an idiot. The time to believe something is when there is sufficient evidence. Trump was pushing (and presumably believing) in HCQ long before there was any good evidence.
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Today Dr Raoults study got through peer review and his 91.7 effective rate held up. Guess the pseudo-science is coming from those who are anxious to find any reason to be negative.
I can already hear the explanations... Dont want to have a rush on the drug because it's already widely used for people with lupus and rheumatoid arthritis, there wasn't enough evidence (even though it was being used all over the world because of its success with SARS), I Dont care Trump bad (#1).
Fact is medical professionals were touting its success but people couldn't get behind it for 1 fricken reason. ....
They are stupid.
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Link to the results?
And what are you comparing the 91.7 percent to? C-19 has a 95+ recovery rate withiut HCQ.
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But thanks for the Post NR it at least shows you want this good information out there.
On the note of a medication being released before approval. The Polio Vaccine was released before approval it was deemed too important NOT to release it as soon as possible.
HcQ being used as a prophylactic by medical professionals was their only defense and MANY use/used it. I have medical professionals in my family that are using it. Anecdotal evidence is STILL EVIDENCE and sounds less approving than it actually is. It doesn't mean dont use it though Gov. Whitner thinks it does. It means more use and study IS warranted.
You people are saying things like "We need to be bold and think bigger" "We need 20,000,000 tests a week". You just out of hand pushed aside a ray of hope because it came from the wrong mouth. That's all Trumps statement on HCQ was. Letting people know that Drs are finding ways to treat this virus... not cure it but give you a fighting chance if you get it.
If you see or hear something else so be it but I feel sorry for you people I really do.
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91.7% efficacy on his 1061 patients.
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That was a good review article, thank you. I recommend everyone take a look at that FASEB article (link posted above). I learned a bunch of new things.
The study I posted is too new to have been in that review article. I'm sure there are additional flaws with it, but it is suggestive of early treatment with hydroxychloroquine, which is an interesting angle to look at and one that has been suggested earlier.
I'm still waiting for that large clinical trial to come out of New York. Hopefully, we'll have results of that soon. Hopefully they will take a look at early intervention of hydroxychloroquine.
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If Trump said Llama plasma may save you would you believe him?
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An observational study is just that, a piece of evidence, but not enough. There's no need to get passive aggressive about this. ""Trump prescribed hydroxychloroquine"", said there was evidence it worked, when in fact there was no conclusive evidence that it worked. That's irresponsible. None of this "Trump bad" shit. The FDA exists for a reason. Clinical trials exist for a reason. To filter out some of the snake oil. If you don't mind corporations paying doctors to give you procedures that are harmful to you can suck on Trump's left titty as a pacifier.
As for hydroxychloroquine, it might work, it might not. We need more evidence. Period.
Trump is also a Dr prescribing drugs? One badass President!
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I have 2 friends both took HCL and recovered in less than 24 hours. In the recommended dosage, there is almost zero downside. I would use it if I had to.
Gilead is donating 1.5m doses of remdesivir stock, not sure about future production.
As for the FDA, they are far from perfect and can be part of the problem, not the solution. Too many horror stories to recount. Don't take anybody's word for anything, do your homework and use some common sense. Stay away from bleach and fish tank cleaner unless recommended by your physician, lol.
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Every time Perfect-Circle says “Trump bad, Trump very bad” I think of the South Park episode with bad Stan.
Ba chomp, ba chomp, ba chewy chewy chomp.
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Um, TOS ^
Let's see if comment disappears or whole blog
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Hopefully, hydroxychloroquine will be shown to be really effective...very available and cheap.
Remdesivir not as widely available and expensive as hell....and what does Fauci get from Gilead if he pushes that drug......?????
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Remdesivir is another weapon in the arsenal if it costs a lot then so be it. IM not playing games about who gets what my only concern is what works, people decrying the use of one drug because the wrong person mentioned it it just bullshit .. I want as many weapons as possible to be used invented and conjured up and I dont care if Nancy Pelosi or Adam Schiff pushes a drug or if Donald Trump does. Is it effective or promising that's all that matters.
Now I'm overdue for my bleach injection and oral dose of pine sol. Have a good day.
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Update: Two new large NY observational studies don't show hydroxychloroquine works against COVID-19. One was published in the New England Journal of Medicine. The other in the Journal of the American Medical Association. Both are respected journals of medicine.
This doesn't look good for hydroxychloroquine. There is a randomized clinical trial coming out eventually. Hopefully that would answer the question of early use.
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There used to be a Pharmaceutical company in Costa Mesa --- where the Van's HQ is now...
I think it was called ICN Pharmaceuticals, they were known for their anti-virus medications and in-depth research facilities... I'm trying to recall some old OC Business Journal articles on ICN, and it seems that they used to combine their anti-viral medications with Ticar or Ticarcillin, and it was very effective against viruses, but I can't remember all of the specifics about ICN Pharmaceuticals, other than they were on the cutting edge of research and bringing anti-viral medications to the market...
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...
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The latest on hydroxychloroquine...
First results of large random clinical trial are out, and hydroxychloroquine did not perform better than placebo at preventing COVID-19 illness.
Hopefully, we'll find out soon with this study if it helps to reduce severity of COVD-19 when people are treated early with it.
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In all honesty I miss waking up at 5am going to my boxing gym.
Engaging in 3 hours of sparring and 2 hours of boxing routines.
This quarantine shit has me all messed up.
My cardio is deteriorating. My bench press, deadlift and squats are at 50% capacity.
Girls have already put a name to my little noticeable gut.
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Welcome @NR. Fact is many of the peer reviewed studies are put together in such a slip shed cherry picked fashion done by quarks who have NO BUSINESS peer reviewing the work I do when I go to the bathroom much less the work done by Dr.s that have used HCQ successfully.
Most of the asshats aren't epidemiologists. Then some other person with an axe to grind picks up a "Trump bad" rant of a study and published in their once prestigious medical rag and shows just how much their hatred for 1 man is, they are willing to take the one thing readily available to be distributed to potential patients and shitcan it. FOOLS, CHARLITANS, LIARS!!!
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Who the fuck are any of you to advocate for ANY drug.? I dont care what your politics are. What reason do you have to push ANY drug.? And why do you think anyone gives a shit about your opinion about ANY drug. You sick bastards.
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^ who gives a shit about your opinion of my opinion on drugs?
Lancet study of 96,000 CV19 cases and HCQ is under review for data and methodology, doesn't look good.
"The Lancet first pulled a study published late last month that found antimalarials provided no benefit as a treatment for Covid-19 infections while increasing the risk of heart problems and death. The New England Journal of Medicine then retracted a separate article, published in early May, that examined the impact of cardiovascular and blood-pressure drugs in Covid-19 patients.
Both articles featured three of the same authors, Mandeep Mehra, Amit Patel and Sapan Desai, and were based on data supplied by Dr. Desai’s company, Surgisphere."
Turns out the data was detritus, the methodology crap and the results were a big biased turd, lol.
That's why so many of you who posted negatively on blogs about HCQ just because Trump mentioned it are full of shit. Let the science work itself out you morons, Trump's opining should matter not one fucking iota.
What the fuck is wrong with you people?
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NEJM retracted the study on ACE blockers having no detrimental effect if you get COVID-19 because their data came from the same group. Their HCQ study still stands.
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Based on the same data and methodolgy from the same company, but you believe what you want..
I'm not saying HCQ is effective, I'm saying jury is still out and science isn't done.
The authors of the New England Journal of Medicine paper said in a statement published on the journal’s website: “We are unable to validate the primary data sources underlying our article.”
"Surgisphere had said it collected the de-identified patient information from hospitals that was used in the studies. The Wall Street Journal contacted more than a dozen large U.S. hospitals, including some that treated high numbers of Covid-19 patients. None said they had an arrangement to share patient data with Surgisphere, and several said they had never heard of it."
In the days following publication of the study, however, other researchers began to raise questions about the Surgisphere data, first on social media and in emails, then in an open letter to The Lancet and the study’s authors. More than 100 researchers signed on to the letter.
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Don't be stupid fuck, they didn't mix Zinc with it.
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Aaahhhh, the magic zinc!
I missed that part.
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Someone cooked the books.....
This is why you almost can't trust ANY study, until you know how is paying for it and what agenda they have......
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who is paying
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Actually one of the Dr.s Sapan Desai in both of those stud
studies is the CEO of Surgispere. C'MON MAN!!
He's authoring studies and on the team publishing the data in the Lancet?!!
Yet the people politicizing the arguement are just Trump supporters?? No no. The politics is HCQ and Covid Started way before Trump said anything about the pandemic.
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NIH just stopped clinical trial of hydroxychloroquine due to finding no benefit with COVID-19 patients.
"A data and safety monitoring board met late Friday and determined that while there was no harm, the study drug was very unlikely to be beneficial to hospitalized patients with Covid-19," the NIH said in a statement.
Still waiting on that early treatment study from University of Minnesota, but it looks like HCQ for COVID is about to be buried 6 feet deep.
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Another Trump success, like Trump steaks.
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Dexamethasone
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There are 44 comments on this blog. This blog is locked and no further comments are permitted. |