| There are 43 comments on this blog. |
|
|
all these studies have a negative bias in them
I am always putting money on who will be the dumbshit to bring the next negative report to the board here
|
|
|
Insearch...yes, far too often people go into a study hoping to get a certain result....and then bad shit happens with the data and true results.....The people conducting the study are being paid by someone....just like an 'expert witness'.....they come to the conclusion of the side who signs the check.
|
|
|
rooting against a 5cent, 70-year-old drug has its own issues
|
|
|
I posted a link to a Dr. Who tweeted about surgisphere and the Lanxet article about a week ago. There is a huge amount of confirmation bias going on with this drug. Clinicians are seeing success with it and Academia and Career government types are trashing it. Who are we to believe?
I know for me rhe subjext of whether HCQ is effextive or mot is not a political question and for those that oppose it who claim its not political for them either I ask why the sudden concern for the "Dangerous" side effects of this widely prescribed well established prescriptiin medication? If I were as concerned about it as much as some I would be trying to get this pulled off the shelves, but to keep it out there and to keep the artificial controversy going only serves one purpose to make someone look bad at the EXPENSE possibly of some lives. They are disingenuous and dangerous the same thing they are accusing those they hate of.
|
|
|
Wow sorry for all the typos AGAIN
|
|
|
Wait for the random clinical trials to all come out. These aren't simply anecdotal (what practitioners *think* they see) or observational. These are well-designed studies where they randomize a sample of a population, give roughly half the medicine, and the other half a placebo, and see if there is a difference in effects. The results from these, if they are designed well, should end the controversy from the viewpoint of science and medicine, maybe not politics.
Results from the first US random clinical trail came out yesterday in the New England Journal of Medicine that hydroxychloroquine does no better than placebo at preventing COVID-19. So that's the word on that. Maybe the medicine has a beneficial early effect when you get COVID-19. We'll have to wait for the results.
|
|
|
i have already seen stuff that knocks that study from a few doctors...yale and some other place...they talked about how the bias of the study sets it up for failure
|
|
|
Clinicians are busy working on saving lives. They are providing results that should at least be recognized but that is not the case, it's sad really.
|
|
|
And so it seems the politics are going to win out....
|
|
|
Science loses again.
|
|
|
Do any of you actually HAVE hydroxychloroquine? Are you actually. going to have to make a decision to take it or not if you get COVID-19?
I have it, and I'm going to listen to the science and not the politics. Waiting for the clinical study to come out, and its verdict will be mine.
Science, not politics.
|
|
|
I swear, 100,000 clinical studies could come out that says this shit is snake oil, and you'll still support it.
|
|
|
So NR you are saying that very experienced epidemiologists can see success where there is none? Can experienced Drs see failure or in efficacy where there was only slight mitigation? Of course.
You got 2 choices in matters of Covid 19 right now. Treat early with HCQ or treat late with Remdesivir. I'm not one to wait and see ... I know what I would prefer.
|
|
|
That's not true... I'm providing valid arguements. All the studies are reporting cherry picked late stage patients. Show me a study that doesn't so far and I'll say different.
|
|
|
I actually agree with you. As of right now, I'd take the HCQ, because there is nothing else early, but that is out of desperation based on hope that worst case it doesn't make me sicker. (I have a portable EKG just to verify heart status anyway).
But, as soon as the clinical study comes out, I'll follow it's verdict.
|
|
|
Studies don't cherry pick late-stage patients. They all use patients that just made it into the hospitals.
|
|
|
Even the studies (not the US ones) that have statistical problems with them use patients in hospitals.
|
|
|
The positive ones I mean.
|
|
|
i am bothered by your energy trying to knock a potential cheap drug down for politics...YOU are the one bringing politics into this and whining about politics winning over science
go fight about police and black men or allowing peaceful looting
|
|
|
BTW I acknowledge the heart arrhythmia effects of HCQ I also believe that it is not that much of a concern for most people.
My big issue with your posts on HCQ are as follows -
You wouldn't take as a prophylactic even though there is nothing else out there to take, even if there was no danger to you if you took it and Doctors are taking it some that dont have faith in it.
You tell us to wait for the peer review studies and anything that has been done has been highly suspect so now we have to wait for the double blind studies and we have to trust that even those results aren't massaged (either way there will be controversy on the subject), the protocol and methods of treatment cant be out of synch with the way clinicians are treating patients.
Your a data guy you dont have any real insight on the drug it's just numbers to you. Clinicians are seeing an effect and you are basically doubting them ... why? There's nothing else.
|
|
|
So if 100,000 studies show the "cheap drug" doesn't work, you'll say the studies are all political?
|
|
|
I cannot believe you just posted that!! The VA study was nothing BUT cherry picked data .... surgisphere Data was if not cherry picked totally made up have you been reading or just arguing?
|
|
|
I doubt the clinicians because they may have an observational bias. They want their patients to get better. Hell, I want HCQ to work too. I have the damn stuff. The blinded random clinical trials should ideally remove all biases.
|
|
|
If 100,000 studies use late stage covid19 patients w comorbidities and the ages are all over 60 I'm calling bullshit.
|
|
|
Forget the Lancet study
There's the New England Journal of Medicine Study.
The JAMA Study
The VA study
The NJ study
That said the same thing and weren't retracted.
|
|
|
"use late stage covid19 patients w comorbidities and the ages are all over 60 I'"
That's not what they used. Period.
|
|
|
"Hell, I want HCQ to work too", then the only thing we have a difference of opinion on is not just the President saying its promising but some clinicians saying it as well. I dont know but believe you think that's irresponsible. I think it's just people talking and in a sense lowering the anxiety levels of the public.
|
|
|
VA study where 3 or 4 of the authors were opthamologists?
|
|
|
There's still hope in the early treatment arm of the clinical studies for HCQ. Let's hope we get some positive result.
|
|
|
here is a nice little paper on it...there is an email to ask him some questions if you need some clarifications
Accepted manuscript
Early Outpatient Treatment of Symptomatic, High-Risk Covid-19 Patients that Should be Ramped-Up Immediately as Key to the Pandemic Crisis
Harvey A Risch
full report...click on pdf on webpage
|
|
|
btw NR...that's the spirit 
|
|
|
Famotidine (Pepcid) is an over-the-counter med that is getting serious attention in possibly preventing hospitalizations and deaths of COVID-19. I've attached the latest on it here.
|
|
|
Additional information on multiple treatments not just HCQ.
I find it extremely credible that when a Dr. Like Dr. Stephen Smith says things as strongly as he is quoted as saying in this article EXTREMELY compelling.
I understand that lab research Drs have their reservations but honestly the nature of their job is to be underwhelmed because everything they see as a possibility for treatment for many many diseases just dont work ... so they suppress expectations... I get it.
Doctors!! The last one you see wont be able to do anything to help ya.
|
|
|
Goddamn CNN!!
Lol is Pepcid AC closely related to Zantac? Do I got to worry about cancer too? I got no HCQ so I guess I'll go with Pepcid. Unless you want to cut me in on some or your stash there NR.
|
|
|
As far as my ability to get HCQ... I can get it if needed, but cough cough... dont need to yet.
|
|
|
I took it 2 different times in my military career. As did tens of thousands of my military brothers and sisters. Liberals are so stupid with TDS that they become mindless.
|
|
|
You will waste a lot of time discussing medical issues with @NR.
He's a "political" scientist. 
A month ago, he said he wouldn't take HCQ under any condition.
Now he's ok with it early on as a last ditch resort
Next he'll be selling it on the street corner
).gif)
|
|
|
Well, the data keeps changing, and so does my opinion.
|
|
|
You've had the data on HCQ sans Covid all the time.
Used for 60 years, on the WHO list of most used and approved drugs, successfully treats malaria, lupus and other diseases, has some known cardiac issues but taken under a doctor's care in prescribed doses is safe and effective.
Still unknown if it successfully treats CV19, but how much can it hurt if door #2 is dying?
The reality is that you're biased, just face it, get over it, and figure out how to fix it. It's not something to be ashamed of, you're human not a robot.
|
|
|
Im sure is the anti hcq anti Trump crowd had covid19.and the doctor said im going to put you hcq it might save your. Wonder many would say well studies have proven its not effective.
|
|
|
Hey hey we got progress here... A man is staying his opinion and reshaping based on evidence and also lack of evidence where it concerns his own safety. Nothing wrong with that!!
Ive objected to posts in the past that totally throw out clinical data in favor of waiting for the controlled studies when we already have evidence that in a large amount of cases there is data to support that HCQ is effective against this virus in the earlier stages .... even a small amount of evidence that its effective FOR SOME after being intubated.
It's not a cure never have I said or read that anyone supporting the use of it as being A CURE. Despite the fact that if I do google search of HCQ Effectivity I get a page and a half of results telling me it's not a cure ... Really??! I didn't think it was in the first place!!!! Thanks Google for not being evil. That's sarcasm.
|
|
|
it's progress
there are more important things to argue about than this drug, but the energy against it pretty much sums up where we are with everything else in our world and being ANTI-trump
hopefully, trump will come out and start pumping beach real estate in Newport and Huntington(maybe get a few places)...the anti-trump people will flee to prove him wrong, knocking prices down 35 percent we still might get there in other ways with what's going on
do it trump
|
|
|
Last I checked Trump is still alive and drawing standard criticism from the leftist media. Just another day
I cant even believe this is a talking point.. but hey
|
| There are 43 comments on this blog. |
