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I'm excited about the science, but not sold at all on HCQ as a treatment. At all. I said what I said after the VA study came out, the two NY studies (one from NEJM and the other from JAMA), and the NJ study. I wouldn't take it in the hospital. I'd prefer remdesivir (if you can get it), convalescent antibody treatment (even harder to get), or dexamethasone (late).
Early treatment? There may be a chance. I'm rooting for it because we have next to nothing. I'd take it at this point (early), not because I believe it will work, but because I think it is relatively harmless (unless you're really ill) and may possibly do something. I'd take the zinc for the same reason with it.
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Meanwhile, watch for favipiravir. There may be something to that for early use at home as well. It's also an anti-viral.
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The mechanism of action is the same as remdesivir.
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mechanism of action...that sounds like someone knows how the drugs work
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Remdesivir and favipiravir are nucleotide base analogs. They can be substituted accidentally during the replication of a virus (production of virus RNA). Multiple substitutions would disrupt the production of viral RNA. Pretty cool trick!
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We're really not sure if that is what happens with COVID-19 however. That's the finding from studying other viruses.
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Holy shit that flew over my head. I dont even know where to look. I'm not going to say you're full of shit because of my ignorance. Or hurl insults. Or blame it on Hillary. I'll take your word on it for now. I guess.
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What other cool tricks you got in your hat, NightRider?
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Better explanation than I gave.
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Meanwhile there’s a shortage of HCQ and people who actually have malaria have no way to be treated 🤔
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My lord, Bougie...those are some Savage boobs.
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Actually, I think the shortages were in March and April. There should be plenty of HCQ to go around now.
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I’m stuck in March for life
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OK, enough about HCQ.
Let's get back to Bougie's boobs...
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Back off, young whippersnapper!
She could be your very well preserved great great great grandmother
She's my generation, I saw her first and I want those breastessess
"I'd take it at this point (early), not because I believe it will work, but because I think it is relatively harmless (unless you're really ill) and may possibly do something"
NR, don't be getting all weasely and shit, k?
That's what we told you to do 2 months ago or more.
Nice little known side effect
HCQ will make your dick harder than Chinese arithmetic
It also cures cancer, dementia and Peyronie's disease
But only if you have all 3 at the same time and catch them early
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"I've just had a third friend who reduced the symptoms big time by taking HCQ and Zinc.
BUT, it seems to work only if taken early on, within 2 - 4 days of onset
102 temp yesterday, 98.6 today"
So it could have been either the HCQ or the Zinc, or neither.
We'll never know because there wasn't a control group.
That's like saying "Vitamin K cures the common cold because I took it for 2 weeks and my cold went away".
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Just a thought.. . but it might be worth actually reading the research and the researcher's own comments rather than just taking a pro-Trump or anti-Trump perspective on a reflexive basis.
The research was NOT RANDOMIZED. . nor was it a DOUBLE BLIND study. Had it been, it would have made the research substantially more significant. Instead, it is merely a call for more research.
The authors specifically note:
Our results also require further confirmation in prospective, randomized controlled trials that rigorously evaluate the safety, and efficacy of hydroxychloroquine therapy for COVID-19 in hospitalized patients. Considered in the context of current studies on the use of hydroxychloroquine for COVID-19, our results suggest that hydroxychloroquine may have an important role to play in reducing COVID-19 mortality.
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the very small trials are very biassed for reason more than just trump
were you in here giving the same spiel when a result was going the other direction?
5cents per pill....1300 per case.
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This drug was determined to be safe and FDA approved decades ago for malaria, rheumatoid arthritis, eczema, and was found to be very effective against SARS. Anyone crying that it’s dangerous is an idiot. Period.
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rooting for the failure of a 5cent drug is what it's about...you can't spin it any other way, so quit trying to
kinda too bad trump attached his name to it with hopefulness
watching Cavuto listen to a positive spin on the drug today and his face was getting sicker and sicker as it went on. after the interview....he had to come out again and talk about the heart risks with taking the drug and wants to make sure people know that to be safe? OK...thanks doctor Cavuto (trump hater)
like any of these doctors don't know what the hell they are doing
again 70 years old...used for lots of things. Do you think the heart issues are a concern with all the other uses it's been used for?
doctors are still using it here and around the world
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"So it could have been either the HCQ or the Zinc, or neither.
We'll never know because there wasn't a control group.
That's like saying "Vitamin K cures the common cold because I took it for 2 weeks and my cold went away"."
Al_Most_Imperfect
I conceded long ago that my experience is anecdotal, not a double blind control group or anything
4 people i know personally have had it
3 recovered using HCQ + Zinc and 1 using nothing
The 3 recoveries happened within 24 to 48 hours of using it, even though they were at different stages from onset.
Some or all could have just recovered without it but maybe not
Given that there's almost no risk, if used under doctor supervision within recommended dosage
Why the fuck wouldn't you use it in the first 4 days onset??
Would you prefer dying cause you hate that Trump used it in a sentence?
Your statement re Vitamin K is a non-sequitur
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In another brand-new retrospective study on risk factors for mortality in patients with COVID-19 in NYC,
hydroxychloroquine was was associated with decreased in-hospital mortality by about 50%.
The study came from Mount Sinai in NYC, which is a very respected institution.
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Initiation, on average, of HCQ treatment was less than a day into hospitalization.
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"Would you prefer dying cause you hate that Trump used it in a sentence?"
I didn't say anything about Trump.
Why does. everything. always. have. to. be. political?
Nevermind. I really don't care.
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I wouldn't worry the whole covid19 per fox is fake yall are good to go
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I would like to spend 30 minutes sucking deep, deep down on Bougie's right tit as I gently, methodically thrust in and out, in and out.
Then the next 30 minutes bearing down hard on her left tit as she grinds away on top of me, in and out, in and out.
Then 5 minutes of Doggie,
Then 5 minutes of Kittie,
Then 5 minutes of Monkey,
Then 5 minutes of Bully.
The Final 10 in 69, the climax leaving our throats smothered in each other's Creme de la Creme.
Oh wait!
Was this blog about HydroxyChloroQuiOhNiNine???.
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You didn't have to use the T word, Al
It was obvious from your silly critique
I got 3 friends that escaped the devil's grip
Using doctor prescribed medicine
Rather than congratulations
You had to say something dumb
Yeah you're right though
Nevermind
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I am still wrestling with the overall idea of COVID.
Before you freak out... I wear a mask. I practice Social Distancing and I am not (yet) a doubter...
But.... when I heard today that we reached 3 million cases... I realized that is less than 1% of the population... and we are entering month 6 or 7 (depending on your math).
137,000 have died (not trying to minimize that) which is less than 5% of the less than 1%.
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Dumbass these numbers are all with massive shutdowns, masks, social distancing etc...... Reqardless of the percentage vs the US population this virus is killing thousands of people. If you say the virus has been here for 6 or 7 months that around 20,000 Americans a month that are dying from it. Also what is not being reported is the thousands of people that have lasting affects from their bout with covid. Some of those affects are life altering.
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Simple answer: A lot more people sick and a lot more deaths if we didn't take precautions.
It's easy to miss that if you can't see it.
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According to an article in Nature, we would have had 4,800,000 more cases by April 6 if we had done nothing. Hospitals would have been inundated. That would have translated to hundreds of thousands more dead from the virus and from the medical system being overrun.
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Summary of paper from Nature.
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They were using Veterans as guinea pigs for that shit at the VA because of the "suggestion" made by the "administration". Veterans died. They determined that it was either ineffective or actually made it worse.
But if bone spurs has convinced you to take those drugs...PLEASE DO SO..then you can make America great again.
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hey dickfuck
the defense department has been handing this drug out for 50 years
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New information may make your Nature article out of date and superfluous
It appears now, from viral strain testing and genetic sequencing, that there are multiple strains of CV2.
D614 strain appears to have left Wuhan as early as November with possible infections from it in multiple cities but due to it being less virulent, it was not picked up and very few died.
G614 is apparently a mutated version that is more virulent and became apparent in Feb/March even though it arrived after D614.
A Chinese study suggests that some Europeans/Americans might have been infected with the milder strain that didn't cause severe symptoms but did create some immunity without necessarily leaving antibodies in its wake.
This may be the reason that some people seem to have "memory" T-cells from past coronavirus infections as detected by the La Jolla Institute for Immunology team from about half of blood samples collected.
Long story short, it's possible that we are closer to herd immunity than believed and that antibody tests may significantly underestimate the number of people who have already been infected with Covid-19, especially if they had the milder strain. This MAY also be the reason why both New York City and Italy seem to have burned out on the infection rate..........may not be due to masks and social distancing.
Although, i have no problem using these tools to slow any spread.
More work needs to be done AND the mask thing is still under hot debate.
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I want to Bougie in Savage's butt.
"Put your Bougie in your butt!
Put, Put...your Bougie in your butt!"
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Sitxie,
You're a total moron who hasn't even looked at the data.
That was a very small study of vets who had it and were within a day or 2 of death anyway, so it was a Hail Mary.......not a study that could be used for anything
Trump lives in your head
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@ Dude.
You just can’t help being a dick.
That’s good for me... so sad for you.
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I read the Wall St. Journal opinion piece, where that sounds like it is from, and the author is wrong.
There was a large new antibody study today that shows that Spain, as hard hit as it was, only has 5% of its population hit by the virus. This tends to be the case for many locations, including Sweden as a whole. Cities have been hit harder. NYC shows 25%. Stockholm about 12.5%. In silico models independently agree with these figures. You can see that for yourself at https://covid19-projections.com.
Even if 30% of the antibodies go undetected, which is what some studies have shown, this means that only 35% of NYC has been hit. Based on what we know, you need 60-80% for herd immunity.
NYC will have to go through at least another round of hell before they even consider being anywhere close to herd immunity.
This is highly speculative, but things have slowed down in NYC, in my opinion, because there is an underlying contact network structure to the spread of any disease including COVID. Network structures is actually what I'm studying right now. Social distancing has helped to break a lot of the connections in this underlying structure, and the 25% of people who have had the disease have further clogged up the network, so there is a bit of a herd effect going on now, but it's temporary and dependent on future social distancing and mask wearing, and if these were to go away, we'd see the virus bounce back in NYC most likely.
What we need is for everyone to take the vaccine once it is ready. Even if the vaccine is only 50% effective, that would bring herd immunity close to the 60% mark, and close to herd immunity. Then we could stop social distancing and mask wearing.
People who don't want to social distance and wear a mask and then not take the vaccine are doing exactly the opposite of what science tells us to do, which will lead to suffering for more people.
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Well maybe you should be writing for the big leagues then since you're so smart?
At least you added this most important part
" in my opinion,"
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Actually, come to think of it, EVERY post in every blog, feed, paper, etc. should add that part
" in my opinion,"
Cause nobody really knows, do they?
You started with 3.5% - 4% infection rates that are now down to .4%
You started with HCQ is like stepping into the gas chamber and now you're like, Yeah I'll give it a go
You've changed your mind so many times, Nobody is quite sure where you stand other than against dying from Covid
Just add " in my opinion" to everything right up front and we're good
).gif)
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^ THE VILLAGE IDIOT ^
4000 new cases today in LA country
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BAM!
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| There are 43 comments on this blog. This blog is locked and no further comments are permitted. |
